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. 2017 Feb 6;39(4):293–301. doi: 10.1590/1516-4446-2016-2015

Table 5. Psychotropics co-prescribed to patients discharged on antipsychotic polypharmacy (APP) and antipsychotic monotherapy (APM) (n=577).

Psychotropic co-prescription Total sample APP APM Test statistic df p-value
Anticholinergic 185 (32.0) 73 (44.5) 112 (27.1) χ2 = 16.30 1 < 0.001
Mood stabilizer
    Sodium valproate 252 (43.6) 87 (3.0) 165 (39.9) χ2 = 8.18 1 0.004
    Lithium 84 (14.5) 16 (9.7) 68 (16.4) χ2 = 4.24 1 0.039
    Lamotrigine 3 (0.5) 1 (0.6) 2 (0.4) Fisher’s exact test - 0.999
    Carbamazepine 3 (0.5) 1 (0.6) 2 (0.4) Fisher’s exact test - 0.999
    Topiramate 1 (0.1) 0 (0) 1 (0.2) Fisher’s exact test - 0.999
Antidepressant
    Amitriptyline 1 (0.1) 0 (0) 1 (0.2) Fisher’s exact test - 0.999
    Clomipramine 1 (0.1) 0 (0) 1 (0.2) Fisher’s exact test - 0.999
    Citalopram 11 (1.9) 2 (1.2) 9 (2.1) Fisher’s exact test - 0.737
    Fluoxetine 21 (3.6) 6 (3.6) 15 (3.6) χ2 = 0.00 1 0.988
    Venlafaxine 2 (0.3) 1 (0.6) 1 (0.2) Fisher’s exact test - 0.488
Benzodiazepine 41 (7.1) 8 (4.8) 33 (7.9) χ2 = 1.72 1 0.189

Data presented as n (%).

APM = antipsychotic monotherapy; APP = antipsychotic polypharmacy; df = degrees of freedom.