. 2016 Jun 8;226:20–39. doi: 10.1016/j.virusres.2016.05.023

Table 1.

Antigenic cross-reactions as determined by CCIF among various strains of PEDV and TGEV using hyperimmune or convalescent pig PEDV and TGEV antisera^a.

	Virus strain^a
Antiserum to PEDV strain and ID number^a	PEDV PC22A, highly virulent	PEDV S INDEL Iowa106	PEDV S 197DEL PC177	PEDV CV777, classic^b	TGEV Miller	TGEV Purdue
Anti-PEDV PC22A-like
PE125 ^d^,^e	2560^c	2560	2560	640	<10	<10
PE276 ^d^,^e	2560	2560	2560	640	<10	<10

Anti-PEDV S INDEL Iowa106
PV109 ^g^,^f	2560	2560	2560	2560	<10	<10
PV151 ^g^,^f	640	640	640	640	<10	<10

Anti-PEDV S 197DEL PC177
PE312 ^d^,^f	640	640	640	640	<10	<10
PE342 ^d^,^f	640	160	640	640	<10	<10

Anti-PEDV CV777
PC13 ^g^,^f^,^b	160	160	160	640	<10	<10
PC14 ^g^,^f^,^b	640	640 ⁵	640	640 ^e	<10	<10

Anti-TGEV Miller
S409 ^d^,^e	640	640	640	640	10,240	10,240
M20 ^d^,^e	160	160	160	160	10,240	10,240

Anti-TGEV Purdue
S411 ^d^,^e	<10	<10	<10	<10	2560	10,240
M2 ^d^,^e	<10	<10	<10	<10	10,240	10,240
RR441 ^d^,^f	<10	<10	<10	<10	640	2560

Negative gnotobiotic (Gn) pig sera (PE71 and HC10078) and mock-inoculated Vero and swine testis (ST) cells were used as negative controls. Data were expressed as the median of sample titrated in triplicates using 4-fold serial dilutions. Detailed materials, methods and data analysis were published in Lin et al. (2015), Journal of Virology 89:3332-3342.

Virus strain and antisera were provided by Dr. Hans Nauwynck (Faculty of Veterinary Medicine, Ghent University, Belgium).

Boldface values represent homologous titers for each PEDV or TGEV strain.

Pig antiserum obtained from gnotobiotic pigs.

Hyperimmune antiserum.

Convalescent antiserum.

Pig antiserum obtained from conventional pigs.