1. Summary of study characteristics.

Study,Country, Design	Participants	Intervention	Outcome measures	Duration
Claesson 1998 Sweden Cluster‐RCT	1854 residents in 33 nursing homes	Multidisciplinary meetings with physician, pharmacist and nurse(s)	Medication‐related problems	14 months
Connolly 2015 Australia Cluster‐RCT	1998 residents in 36 nursing homes	Multidisciplinary meetings with study geriatrician, a GP, a pharmacist and a nurse manager. Education of nurses and care‐givers	Hospital admissions Mortality	14 months
Crotty 2004a Australia Cluster‐RCT	154 residents in 10 nursing homes	Multidisciplinary case conferencing with GP, a geriatrician, a pharmacist, residential care staff and an Alzheimer's Association representative	Medication Appropriateness Index	3 months
Crotty 2004b Australia Patient‐RCT	110 patients discharged to 85 long‐term care facilities	Pharmacist transition co‐ordinator. Transfer of medicines information to nursing staff, family physician and community pharmacist plus medication review and case conferencing	Adverse drug events Hospital admissions Medication‐related problems Medication Appropriateness Index	8 weeks
Frankenthal 2014 Israel Patient‐RCT	359 residents in 1 chronic care geriatric facility	Medication review by the study pharmacist	Hospital admissions Mortality Quality of life Medication appropriateness (STOPP‐START) Medication‐related problems Medicine costs	12 months
Furniss 2000 UK Cluster‐RCT	330 residents in 14 nursing homes	Medication review by a single pharmacist	Hospital admissions Mortality Medication‐related problems Medicine costs	8 months
Garcia‐Gollarte 2014 Spain Cluster‐RCT	716 residents in 36 nursing homes	Physician educational programme followed by on‐demand support (prescription advice) by phone	Hospital admissions (total number of days spent in hospital) Medication appropriateness (STOPP‐START)	6 months
Gurwitz 2008 USA/Canada Cluster‐RCT	1118 residents in 29 units in 2 long‐term care facilities	Computerised provider order entry with clinical decision support	Adverse drug events	12 months
Pitkala 2014 Finland Cluster‐RCT	227 residents in 20 assisted living facilities	Nurse training and education	Hospital admissions Mortality Health‐related Quality of Life Medication appropriateness (Beer's criteria plus others)	12 months
Roberts 2001 Australia Cluster‐RCT	3230 residents in 52 nursing homes	Introduction of new professional role, nurse education and medication review by pharmacists	Hospital admissions Mortality Medication‐related problems Medicine costs	24 months
Strikwerda 1994 Netherlands Cluster‐RCT	196 residents in 1 nursing home	Feedback on GP prescribing from community pharmacist	Medication‐related problems	6 weeks
Zermansky 2006 UK Patient‐RCT	661 residents in 65 care homes	Medication review by a single pharmacist	Hospital admissions Mortality Medication‐related problems Medicine costs	6 months