Brumley 2007.

Methods	RCT
Participants	Age: Mean 74 years, SD 12.0 Sex: 51% men (n = 151), 49% women (n = 146) Ethnicity: 37% belonged to an ethnic minority group; 18% were Asian/Pacific Islanders, 13% Hawaiian, 4% Latino, 2% other Place of residence: 66% lived in their own home or apartment; 8% lived in the home of a family member; 74% resided with a family member, primarily a spouse or a child; 26% lived alone Condition: Late‐stage COPD (21%), CHF (33%), or cancer (47%) and a life expectancy of 12 months or less; participants visited the emergency department or hospital at least once within the previous year; and scored 70% or less on the Palliative Performance Scale. The primary care physician assessed life expectancy, responding to the question 'Would you be surprised if this patient died in the next year?' Number recruited: 718 referred to the study, 408/718 excluded: 196 did not meet eligibility criteria, 67 were eligible for and admitted to hospice care, 59 refused, 38 died before enrolment, 26 were part of another research project, and 22 moved out of the area or could not be contacted. 310 terminally ill participants were randomly allocated: T = 155, C = 155. 8/155 in the intervention group died before receiving palliative care, while in the control group 5/155 withdrew from the study. This left 297 available for analysis
Interventions	Multidisciplinary team including a physiotherapist, occupational therapist, speech therapist, dietitian, social worker, bereavement co‐ordinator, counsellor, chaplain, pharmacist, palliative‐care physician, and a specialist nurse trained in symptom control and biopsychosocial interventions. The specialist nurse provided education, discussed goals of care and the expected course of the disease and expected outcomes, as well as the likelihood of success of various treatment and interventions. 24‐hour care was available if required The service was co‐ordinated by a core team of physician, specialist nurse, and social worker who managed care across settings and provided assessment, evaluation, planning, care delivery, follow‐up, monitoring, and continuous reassessment of care. The service was not time‐limited and was provided until death or transfer to a hospice Control care: followed Medicare guidelines, services included home health services, acute care services, primary care services, and hospice care
Outcomes	Reid‐Gundlach Satisfaction with Services instrument was used to measure overall satisfaction with services, perception of service providers, and likelihood of positive recommendations of services to others. Palliative Performance Scale was used to measure severity of illness Data were also collected retrospectively from HMO service utilisation databases at each site, from time participant enrolled in study until time of death or end of study period. Medical service use data: costs for all standard medical care and costs associated with the palliative‐care programme. Service data: number of emergency department visits, physician office visits, hospital days, skilled nursing facility days, home health and palliative visits, palliative physician home visits, and days in hospice. Service costs calculated using actual costs for contracted medical services (Colorado) and proxy cost estimates for all services provided within the HMO
Notes	Healthcare system: US healthcare system, not‐for‐profit HMOs. 2‐group model, closed panel, non‐profit HMOs providing integrated healthcare services in Hawaii and Colorado. The Colorado site has more than 500 physicians representing all medical specialities and subspecialities in 16 separate ambulatory medical offices spread across a greater metropolitan area. The HMO contracts with outside providers for emergency department, hospital, home health, and hospice care to serve its 477,000‐person membership, which spans the 6‐county Denver metropolitan area. The Hawaii site is located in Oahu and serves approximately 224,000 members, with 12 medical offices in Oahu, 3 in Maui, and 3 on the Big Island. A medical group of 317 physicians provide care. In contrast to Colorado, the HMO provides all outpatient and most inpatient care, and it also has an internal home health agency
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	Group assignment was determined by blocked randomisation using a computer‐generated random number chart, stratified according to study site
Allocation concealment (selection bias)	Low risk	Once eligibility was determined, the intake clerk contacted the evaluators, who randomly assigned participants to the palliative‐care intervention or to usual care
Blinding (performance bias and detection bias) All outcomes	High risk	Participants and clinical staff were aware of the intervention; the researchers employed research assistants who were blinded to the group assignments and collected data by telephone
Incomplete outcome data (attrition bias) All outcomes	Low risk	8/155 died in the intervention group before the intervention was delivered; 5/155 withdrew from the control group During the course of the study (maximum follow‐up time at 120 days), 75% (n = 225) participants died
Selective reporting (reporting bias)	Unclear risk	No information
Baseline measures	Low risk	Palliative Performance Scale, demographic data similar between groups
Protection against contamination	Low risk	Both groups had access to hospice care; the control group did not have access to the intervention (an interdisciplinary home‐based healthcare programme)