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Inhibitory effect of 4-modified sialosides 1 and 2 on the 4-SOAE enzymes from MHV-S and SDAV.
| Sialoside concentration | MHV-S |
SDAV-HE |
||
|---|---|---|---|---|
| 1 | 2 | 1 | 2 | |
| 0.1 mM | 4.00%a | 5.00% | 2.13% | 8.30% |
| 0.5 mM | 0% | 2.36% | 2.56% | 2.89% |
| 1 mM | 8.31% | 11.89% | 0.51% | 0.65% |
| 5 mM | 7.73% | 7.81% | 8.73% | 10.96% |
Inhibition (in %) of 4-SOAE-catalysed hydrolysis of p-nitrophenyl acetate.
