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. 2019 Aug 23;144(6):1551–1565.e2. doi: 10.1016/j.jaci.2019.08.010

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© 2019 American Academy of Allergy, Asthma & Immunology.

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Fig 6 — A, Distribution of TLR3 (a, b, c, and d) and TLR7 (e, f, g, and h) in normal sinus mucosal tissue (NE; a and d) and inflammatory sinus mucosal tissue from patients with CRSsNP (b and f), patients with noneosinophilic CRSwNP (nCRSwNP; c and g), and patients with eosinophilic CRSwNP (eCRSwNP; d and h). Arrowheads indicate superficial epithelial cells, small arrows indicate blood vessels, and large arrows indicates glands. Original magnification ×200. B and C, Levels of TLR3 and TLR7 mRNA transcripts and proteins were evaluated by using real-time PCR (Fig 6, B) and Western blotting (Fig 6, C). NS, No statistical significance. Data from 7 independent experiments are presented as means ± SEMs.