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. 2020 Apr 1;145(4):e20192114. doi: 10.1542/peds.2019-2114

TABLE 3.

RR and 95% CIs for the Association of non–HDL-C and LDL-C Status in Youth With Carotid Artery IMT ≥90th Percentile in Adulthood Stratified by Youth Age Group (n = 4582)

Youth Age Group, ya
38 911 1214 1517 18+
n Out of Nb % RR (95% CI) n Out of Nb % RR (95% CI) n Out of Nb % RR (95% CI) n Out of Nb % RR (95% CI) n Out of Nb % RR (95% CI)
NonHDL-C
 Normal 117 out of 633 18.5 Reference 54 out of 392 13.8 Reference 77 out of 627 12.3 Reference 47 out of 342 13.7 Reference 7 out of 104 6.7 Reference
 Elevated 45 out of 371 12.1 0.89 (0.63–1.24) 28 out of 238 11.8 0.95 (0.61–1.49) 31 out of 240 12.9 1.27 (0.83–1.95) 25 out of 191 13.1 1.11 (0.70–1.75) 19 out of 119 16.0 2.43 (1.10–5.38)c
 Dyslipidemia 68 out of 477 14.3 1.10 (0.80–1.52) 45 out of 280 16.1 1.42 (0.92–2.20) 34 out of 263 12.9 1.36 (0.91–2.03) 32 out of 177 18.1 1.72 (1.08–2.72)c 18 out of 130 13.9 2.20 (0.98–4.94)
LDL-C
 Normal 116 out of 629 18.4 Reference 56 out of 398 14.1 Reference 86 out of 673 12.8 Reference 49 out of 359 13.7 Reference 10 out of 119 8.4 Reference
 Elevated 34 out of 296 11.5 0.84 (0.59–1.21) 25 out of 188 13.3 1.05 (0.66–1.67) 21 out of 190 11.1 1.04 (0.65–1.66) 20 out of 169 11.8 1.08 (0.66–1.77) 19 out of 102 18.6 2.25 (1.12–4.55)c
 Dyslipidemia 80 out of 556 14.4 1.15 (0.85–1.57) 46 out of 324 14.2 1.24 (0.80–1.92) 35 out of 267 13.1 1.35 (0.90–2.03) 35 out of 182 19.2 1.97 (1.24–3.15)c 15 out of 132 11.4 1.40 (0.66–2.99)

All analyses were adjusted for age, BMI, and systolic blood pressure at baseline, sex, cohort, and length of follow-up.

a

The age when non–HDL-C or LDL-C levels were first measured in youth.

b

Number of participants with high IMT out of all participants.

c

Statistical significance, P < .05.