TABLE 4.
RR and 95% CIs for the Association of non–HDL-C and LDL-C Status in Youth With Carotid Artery IMT ≥90th Percentile in Adulthood by Cohorts (n = 4582)
| CDAH | Bogalusa | Insulin Study | YFS | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| n Out of Na | % | RR (95% CI) | n Out of Na | % | RR (95% CI) | n Out of Na | % | RR (95% CI) | n Out of Na | % | RR (95% CI) | |
| Non–HDL-C | ||||||||||||
| Normal | 48 out of 234 | 20.5 | Reference | 177 out of 1068 | 16.6 | Reference | 34 out of 209 | 16.3 | Reference | 43 out of 586 | 7.3 | Reference |
| Elevated | 20 out of 107 | 18.7 | 0.88 (0.55–1.41) | 25 out of 150 | 16.7 | 0.96 (0.66–1.39) | 8 out of 43 | 18.6 | 0.85 (0.38–1.87) | 95 out of 859 | 11.1 | 1.51 (1.07–2.14)b |
| Dyslipidemia | 16 out of 60 | 26.7 | 1.21 (0.74–1.99) | 11 out of 74 | 14.9 | 0.71 (0.41–1.22) | 2 out of 33 | 6.1 | 0.27 (0.07–1.11) | 168 out of 1159 | 14.5 | 1.92 (1.39–2.65)b |
| LDL-C | ||||||||||||
| Normal | 51 out of 248 | 20.6 | Reference | 178 out of 1075 | 16.6 | Reference | 38 out of 234 | 16.2 | Reference | 50 out of 620 | 8.1 | Reference |
| Elevated | 15 out of 85 | 17.7 | 0.85 (0.51–1.42) | 23 out of 140 | 16.4 | 0.93 (0.63–1.38) | 5 out of 32 | 15.6 | 0.65 (0.28–1.49) | 76 out of 688 | 11.1 | 1.41 (1.00–1.97)b |
| Dyslipidemia | 18 out of 68 | 26.5 | 1.20 (0.74–1.93) | 12 out of 77 | 15.6 | 0.75 (0.44–1.25) | 1 out of 19 | 5.3 | 0.26 (0.04–1.92) | 180 out of 1296 | 13.9 | 1.70 (1.26–2.29)b |
All analyses were adjusted for age, BMI, and systolic blood pressure at baseline, sex, cohort, and length of follow-up.
a
Number of participants with high IMT out of all participants.
b
Statistical significance, P < .05.