Table 3. 2019-nCoV 9-mer peptides predicted to bind 4 different HLA alleles by NetMHCpan 4.0, and those predicted to bind ≥ 3 HLA alleles and immunogenicity score ≥ 0.9 by iPred.
For different alleles, 0 denotes non-binding and 1 denotes binding predicted for specific HLA allele.
| Antigen.epitope | Imm.prob | A0101.NB | A0201.NB | B0702.NB | B4001.NB | C0702.NB | Total
binding HLA |
|---|---|---|---|---|---|---|---|
| VQMAPISAM | 0.893938 | 0 | 1 | 1 | 1 | 1 | 4 |
| AMYTPHTVL | 0.862427 | 0 | 1 | 1 | 1 | 1 | 4 |
| TLDSKTQSL | 0.254998 | 1 | 1 | 1 | 0 | 1 | 4 |
| KVDGVVQQL | 0.191786 | 1 | 1 | 1 | 0 | 1 | 4 |
| KVDGVDVEL | 0.18632 | 1 | 1 | 1 | 0 | 1 | 4 |
| MADQAMTQM | 0.991227 | 1 | 0 | 1 | 0 | 1 | 3 |
| LEAPFLYLY | 0.983072 | 1 | 0 | 0 | 1 | 1 | 3 |
| RTAPHGHVM | 0.972153 | 1 | 0 | 1 | 0 | 1 | 3 |
| IPFAMQMAY | 0.961569 | 1 | 0 | 1 | 0 | 1 | 3 |
| FLTENLLLY | 0.951715 | 1 | 1 | 0 | 0 | 1 | 3 |
| YLQPRTFLL | 0.947743 | 1 | 1 | 0 | 0 | 1 | 3 |
| MMISAGFSL | 0.941318 | 0 | 1 | 1 | 0 | 1 | 3 |
| ATLPKGIMM | 0.926603 | 1 | 0 | 1 | 0 | 1 | 3 |