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. 2020 Mar;30(3):406–414. doi: 10.1101/gr.241687.118

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© 2020 Luo et al.; Published by Cold Spring Harbor Laboratory Press

This article is distributed exclusively by Cold Spring Harbor Laboratory Press for the first six months after the full-issue publication date (see http://genome.cshlp.org/site/misc/terms.xhtml). After six months, it is available under a Creative Commons License (Attribution-NonCommercial 4.0 International), as described at http://creativecommons.org/licenses/by-nc/4.0/.

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Figure 3. — TAD-like structures in the MIC of T. thermophila. (A) Compartment eigenvector of Smc1-HA HiChIP was plotted along Chromosome 3 of the MIC for three different conjugation stages and used as A (red) and B (blue) compartments segmentation. (B) Heatmaps showing the chromosome interactions on Chromosome 3 (50-kb bin) at three different times during conjugation (Smc1-HA HiChIP data, from left to right: 1.5 hpm, 3 hpm, and 24 hpm). Zoomed-in views (5-kb bin) are shown at the bottom. Numbers at the lower left of heatmaps correspond to the maximum signal in the matrix. (C) The number of chromatin domains found by HiCExplorer with HiChIP data of the three different conjugation stages.