Table 4.
Screening tests for donor organs
| Tests | Comments/Action Required for Abnormal Results |
|---|---|
| HIV-1 and 2 | Positive test contraindicates organ use |
| HTLV-1 and 2 | Positive test contraindicates organ usea |
| Hepatitis A virus | Positive IgM contraindicates organ use |
| Hepatitis B virus | Obtain full panel of hepatitis B serology, including surface antigen and anti-core antibody; positive HBsAg contraindicates organ use |
| Hepatitis C virus | Some centers use positive organ only for positive candidates |
| CMV | Obtain IgG; urine culture for seropositive infants <2 years |
| EBV | Viral capsid antigen and EBNA |
| Toxoplasma gondii | Obtain on heart, heart-lung donor |
| Treponema pallidum | Positive confirmatory test contraindicates organ use |
Abbreviation: HBsAg, hepatitis B surface antigen.
This is currently being reexamined in some jurisdictions given lack of availability of testing platforms.