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. 2015 Dec 3;488:232–241. doi: 10.1016/j.virol.2015.11.011

Fig. 4.

Fig. 4.

Transcriptional regulation of innate viral sensing molecules in chicken embryo kidney (CEK) cells at 9 and 24 hpi (hours post-infection). Relative mRNA expression of (A) LGP2, (B) MDA5, (C) TLR1, (D) TLR2, (E) TLR3, (F) TLR7 in CEK cells infected with IBV strains 885, QX, or M41 at MOI 1.0 and gene expression was analysed at 9 and 24 hpi. Relative mRNA expression was determined by real-time PCR, normalised to 18S rRNA. Graph values are the mean of three biological replicates with error bars as standard error and are expressed as fold change relative to the mocked-infected group. Different letters indicate that the differences between groups at that time point are significant (p<0.05).