Table 1.

Serum neutralizing and SARS-S specific ELISA IgG antibody responses following intranasal and intratracheal administration of SARS-CoV^a

Monkey		Serum antibody titer on indicated day
			Neutralizing Ab		ELISA Ab
Species	ID #	Day 0	Day 28	Day 0	Day 28
Rhesus	97	<1:8b	1:37c	1:640	1:10240
	9R	<1:8	1:18	1:640	1:2560
	8V	<1:8	1:17	1:640	1:2560
	6K	<1:8	1:36	1:2560	1:10240
Cynomolgus	18	<1:8	1:32	1:640	1:10240
	1806	<1:8	<1:8	1:640	1:2560
	396	<1:8	1:16	1:640	1:10240
	972	<1:8	1:71	1:160	1:40960
African Green	V130	<1:8	1:35	1:2560	1:40960
	V131	<1:8	1:64	1:2560	1:10240
	V240	<1:8	1:64	1:640	1:10240
	V304	<1:8	1:64	1:640	1:10240

^aMonkeys received 1 ml each of 10⁶ TCID₅₀ of SARS-CoV by intranasal and intratracheal administration on day 0 and sera were collected before virus administration and 28 days later.

^bSera were tested starting with a dilution of 1:8. Serum samples that did not neutralize virus infectivity at the starting dilution were assigned a titer of 1:4 in determining four-fold rises.

^cFour-fold rises in titer are indicated in bold type.