Fig. 5.
Kinetics of primary CD8+ T cell responses to vJS510 infection in IL-15−/− mouse. Splenocytes from naïve and vJS510-infected wt (B6, gray bars) and IL-15−/− mice (white bars) were analyzed for CD44 (A) and CD122 (B) expression on CD8+ T cells at the indicated time points pi. Each full-length bar represents the average percentage of CD8+ T cells within total splenocytes. The portion of CD44hi CD8+ T cells or CD122hi CD8+ T cells, respectively, is indicated by striped portions in each bar. SD were below 10% of the average and are not shown. (C) Bars indicate total numbers of CD122hi CD8+ T cells per spleen ± SD (n = 3–4 mice).