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. 2014 Dec 12;56(5):666–673. doi: 10.1016/j.tetlet.2014.12.012

Table 5.

Synthesis of 3-hydroxy-3-indolylindoline-2-ones in the presence of β-CD-SO3H in water at reflux tempa

graphic file with name fx6.jpg

Sr. No. Isatin Indole Product Time (min) Yieldb (%)
3a graphic file with name fx7.gif graphic file with name fx8.gif graphic file with name fx9.gif 5 86
3b graphic file with name fx10.gif graphic file with name fx11.gif graphic file with name fx12.gif 5 92
3c graphic file with name fx13.gif graphic file with name fx14.gif graphic file with name fx15.gif 15 88
3d graphic file with name fx16.gif graphic file with name fx17.gif graphic file with name fx18.gif 5 96
3e graphic file with name fx19.gif graphic file with name fx20.gif graphic file with name fx21.gif 10 86
3f graphic file with name fx22.gif graphic file with name fx23.gif graphic file with name fx24.gif 5 88
a

Reaction condition: isatin (1.0 mmol), indole (1.0 mmol), β-CD-SO3H (0.1 mmol), water (2 mL).

b

Isolated yield.