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. 2006 Jun 21;353(1):6–16. doi: 10.1016/j.virol.2006.03.049

Fig. 1.

Fig. 1

Schematic diagram of S protein of SARS-CoV and pRBD-AAV. The structure of SARS-CoV S protein (A). In the S1 domain, SP and RBD range from 1 to 13 aa (13 aa) and from 318 to 510 aa (193 aa), respectively. The S2 domain contains functional domains HR1, HR2 and TM. DNA encoding 24 aa of the CD5 signal peptide and 193 aa RBD of SARS-CoV S protein was amplified and ligated into the pAAV-IRES-hrGFP plasmid to construct the recombinant pRBD-AAV vector (B).