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Clustering and general features of the 5′ 420 nucleotides of CoVs. The tree is based on a multiple sequence alignment using ClustalW2 at the European Bioinformatics Institute webserver. The phylogenetic group, the start of core TRS-L, the region of upstream ORF (uORF), the start of ORF1ab, and GenBank accession number of each CoV are listed.
