Fig. 4.
PEDV-specific humoral responses in sows and piglets. Pregnant sows were vaccinated with VSVMT-SΔ19 or PBS three times on days 0, 14, and 28 as indicated by arrows. (A) PEDV-specific virus neutralizing (VN) antibody titers in sera from sows collected at the indicated time points post-inoculation. (B) VN antibody titers in the whey of colostrum or milk collected from sows at the indicated timepoints. (C) VN antibody titers of the sera collected from piglets that suckled vaccinated or control sow milk for 5 days before virulent PEDV challenge. Statistical analyses were performed using an unpaired two-tailed t-test; data are presented as means ± SD. *p < 0.05 and **p < 0.01.