Fig. 2.
Extrapulmonary pathology of SARS. A, Reactive hemophagocytosis in pulmonary hilar lymph node. B, Reactive hemophagocytosis in bone marrow. C, Lymphoid depletion in spleen. D, Skeletal muscle fiber necrosis. E, Acute tubular necrosis of kidney compared with normal tubule at left upper corner. F, Mitosis and apoptosis of hepatocytes (arrowheads) and ballooning degeneration in SARS-CoV–associated hepatitis (hematoxylin-eosin stain, original magnification ×1000 [A and B] and ×400 [all others]; A and B taken from a patient with SARS dying on day 18; C-E taken from a patient with SARS dying on day 20; F taken from liver biopsy of a patient with SARS on day 31).