Fig. 7.

Humoral immune response elicited by rTGEV expressing PRRSV antigens. (A) Humoral response specific for GP5. Serum samples were collected at the indicated times post-immunization and analyzed by ELISA using purified full-length GP5. Dots represent individual animals and solid lines represent mean titer of each group. The arrow indicates the time when challenge was performed. ^⁎⁎⁎, p-value<0.01; ^⁎⁎, p-value<0.05. (B) Neutralizing antibodies induced at the indicated times post-challenge. Neutralization assays were performed with PRRSV Olot91 strain infecting MARC-145 cells. Dots represent individual animals and solid lines represent mean titer of each group. ^⁎, p-value<0.1.