Table 2.

Main results of bioinformatic analysis.

	Q4 (the quantile with high L/H ratio)	Q1(the quantile with low L/H ratio)
Biological process	Multiple stimuli (e.g., extracellular, stress, oxygen levels, inorganic substances), lipid metabolism, extracellular structure organization, reactive oxygen species and organic hydroxy species metabolic responses, immune and defense responses	Chromosomal segregation and cell divison, primary and macromolecular metabolic processes
GO-molecular functions	Various transmembrane transporter activities	Nucleic acid processing
GO-cellular compartment	Membranes (e.g., Golgi apparatus, endosomes, MHC class molecules, organelle membranes, plasma membrane, nuclear outer membrane)	Nucleus, chromosomes, ribosomes, and minichromosome maintenance (MCM) complex
Protein domain	Immune competence (e.g., MHC class molecules and immunoglobulins)	Nucleic acid processing (e.g., helicase, nucleotide-binding, RNA recognition, exoribonuclease, and transcription regulation [SNF2-related and COMM domains])
KEGG pathway	Phospatidylinositol signaling, GABAergic synapse, cell adhesion molecules (CAMs), glycerophospholipid metabolism, and immune response pathways (e.g., antigen processing and presentation, autoimmune thyroid disease, allograft rejection, graft-versus-host disease)	Nucleic acid, cell cycle, ribosomal processes, purine and pyrimidine metabolism
Protein complex	Two protein complexes related to mitochondrial protein transport and interferon signaling	17 protein complexes related to DNA replication, DNA repair response, chromosome shape regulation