Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Mar 25;11:431. doi: 10.3389/fimmu.2020.00431

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2020 Grødeland, Baranowska-Hustad, Abadejos, Blane, Teijaro, Nemazee and Bogen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Antibodies and protective efficacy after vaccination with αMHCII-H1stem and MIP1α-H1stem. BALB/c mice (n = 10 mice/group) were DNA-immunized twice on days 0 and 29, as indicated by arrows. (A) Sera were analyzed for development of total IgG responses against recombinant HA from PR8 and A/Hong Kong/483/97 (H5N1) and IgG1/IgG2a against HA from PR8. Values given are mean ± SEM. *p < 0.05 as compared to NaCl (two-way ANOVA and Bonferroni post-test). (B) 4 weeks after the final vaccination, mice were challenged with a 5 × LD50 dose of influenza PR8 and monitored for weight loss.