TABLE 2.

Heritabilities of lipid classes

Lipid Class (Abbreviated Name)	Lipid Class (Full Name)	n	h2 (SE)a	P	q-Value
dhCer	Dihydroceramide	6	0.35 (0.04)	9.5 × 10−27	2.4 × 10−26
Cer(d)	Ceramide	40	0.34 (0.04)	3.6 × 10−25	7.0 × 10−25
HexCer	Monohexosylceramide	14	0.50 (0.04)	7.2 × 10−47	1.2 × 10−45
Hex2Cer	Dihexosylceramide	10	0.45 (0.04)	3.1 × 10−42	3.4 × 10−41
Hex3Cer	Trihexosylceramide	6	0.43 (0.04)	2.5 × 10−35	2.0 × 10−34
SM	Sphingomyelin	36	0.36 (0.04)	4.4 × 10−27	1.2 × 10−26
GM1	GM1 ganglioside	1	0.28 (0.04)	2.5 × 10−18	3.2 × 10−18
GM3	GM3 ganglioside	7	0.40 (0.04)	2.7 × 10−29	1.0 × 10−28
Sulf	Sulfatide	6	0.40 (0.04)	1.8 × 10−32	1.2 × 10−31
PC	Phosphatidylcholine	68	0.36 (0.04)	8.1 × 10−26	1.7 × 10−25
PC(O)	Alkylphosphatidylcholine	21	0.34 (0.04)	5.5 × 10−25	1.0 x 10−24
PC(P)	Alkenylphosphatidylcholine	24	0.40 (0.04)	1.1 × 10−31	6.1 × 10−31
LPC	Lysophosphatidylcholine	56	0.29 (0.04)	3.4 × 10−17	3.9 × 10−17
LPC(O)	Lysoalkylphosphatidylcholine	10	0.31 (0.04)	1.5 × 10−19	2.0 × 10−19
LPC(P)	Lysoalkenylphosphatidylcholine	4	0.33 (0.04)	4.2 × 10−24	6.9 × 10−24
PE	Phosphatidylethanolamine	36	0.34 (0.04)	7.3 × 10−26	1.6 × 10−25
PE(O)	Alkylphosphatidylethanolamine	14	0.27 (0.04)	1.7 × 10−17	2.0 × 10−17
PE(P)	Alkenylphosphatidylethanolamine	54	0.29 (0.04)	1.4 × 10−18	1.9 × 10−18
LPE	Lysophosphatidylethanolamine	14	0.38 (0.04)	8.1 × 10−30	3.3 × 10−29
LPE(P)	Lysoalkenylphosphatidylethanolamine	4	0.31 (0.04)	2.2 × 10−21	3.2 × 10−21
PG	Phosphatidylglycerol	4	0.36 (0.03)	3.7 × 10−31	1.7 × 10−30
PI	Phosphatidylinositol	27	0.35 (0.04)	3.5 × 10−26	8.1 × 10−26
LPI	Lysophosphatidylinositol	8	0.27 (0.04)	3.4 × 10−16	3.8 × 10−16
PS	Phosphatidylserine	7	0.16 (0.03)	4.0 × 10−7	4.1 × 10−7
COH	Cholesterol	1	0.26 (0.04)	5.9 × 10−15	6.3 × 10−15
CE	Cholesteryl ester	28	0.38 (0.04)	7.2 × 10−29	2.2 × 10−28
DE	Dehydrocholesterol ester	6	0.28 (0.04)	1.2 × 10−17	1.5 × 10−17
oxCE	Oxidized cholesteryl esters	2	0.14 (0.04)	7.1 × 10−6	7.1 × 10−6
AC	Acylcarnitine	14	0.48 (0.03)	2.0 × 10−50	6.6 × 10−49
DG	Diacylglycerol	20	0.31 (0.03)	1.3 × 10−22	2.1 × 10−22
TG	Triacylglycerol	44	0.32 (0.03)	1.6 × 10−24	2.7 × 10−24
TG(O)	Alkyl-diacylglycerol	3	0.37 (0.04)	6.4 × 10−29	2.1 × 10−28
CoQ10	Ubiquinone	1	0.29 (0.04)	1.7 × 10−20	2.5 × 10−20
Total		596

Lipid classes presented in this table were calculated by summing the lipid species within each class. n, number of lipid species within class; h², heritability.

^aHeritability estimates adjusted by age, age², sex, sex × age, sex × age², and using lipid-lowering medication-adjusted values.