Fig 1. Speed of killing for Entamoeba histolytica.
Results from experiment to assess kinetics of drug action against E. histolytica trophozoites. Drugs were assayed at the following concentrations (2x the previously measured EC50 [6]): metronidazole, 17μM; auranofin 0.5μM; anisomycin, 1.4μM; prodigiosin, 1.4μM; obatoclax, 1μM; nithiamide, 10μM. Graph shows FDA signal as a percent of DMSO control. Killing was assayed at 10, 24 and 48 hours, and three biological replicates were performed for each data point.