Table 4.

Outpatient treatment of community-acquired pneumonia

Presence of Comorbidities	Antibiotic Choice
NO	Macrolide or doxycycline
YES	Fluoroquinolone or beta-lactam + macrolide (doxycycline is an alternative for macrolide)

Comorbidities: chronic heart; lung, liver, kidney disease; diabetes; cancer; impaired immune system; alcoholism; asplenia; recent use of antibiotics in previous 3 mo; and risk for multidrug-resistant S. pneumoniae.

Adapted from Mandell L, Wunderink R, Anzueto A, et al. Infectious Diseases Society of America/American Thoracic Society consensus guidelines on the management of community-acquired pneumonia in adults. Clin Infect Dis 2007;44(Supplement 2):S45.