Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2009 Aug 18;73:99–170. doi: 10.1016/S0065-3527(09)73003-9

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2009 Elsevier Inc. All rights reserved.

Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

PMC Copyright notice

Possible models of circularization. (A) Closed-loop model or circularization of cellular mRNAs. eIF4E+eIF4G+eIF4A, eIF4F complex; Stop, termination codon. (B) Models of circularization of Poliovirus genome. CL, cloverleaf structure; 3C and 3CD, viral proteases. (C) Role of rotavirus NSP3 in mRNA circularization. NSP3 mediates viral mRNA circularization (left) and inhibits cellular mRNA circularization (right). N and C, N- and C-terminal regions of proteins; TE, translation enhancer. Dashed arrows indicate interactions between proteins. Other indications are as in legend of Fig. 1.

Possible models of circularization. (A) Closed-loop model or circularization of cellular mRNAs. eIF4E+eIF4G+eIF4A, eIF4F complex; Stop, termination codon. (B) Models of circularization of Poliovirus genome. CL, cloverleaf structure; 3C and 3CD, viral proteases. (C) Role of rotavirus NSP3 in mRNA circularization. NSP3 mediates viral mRNA circularization (left) and inhibits cellular mRNA circularization (right). N and C, N- and C-terminal regions of proteins; TE, translation enhancer. Dashed arrows indicate interactions between proteins. Other indications are as in legend of Fig. 1.