Table 6.
Clinical and pathologic findings of seven severe acute respiratory syndrome (SARS) patients undergoing postmortem examination
Case number | Gender/age | SARS confirmed by polymerase chain reaction | Kidney confirmed by light microscopy | Benign nephrosclerosis | Viral particles by electron microscopy | Autolysis | Plasma creatinine at presentation μmol/L | Plasma creatinine at the time of death μmol/L | Postmortem cause of death |
---|---|---|---|---|---|---|---|---|---|
1 | M/69 | Yes | Moderate acute tubular necrosis | + | Not detected | Yes | 100 | 258 | Diffuse alveolar damage |
2 | M/64 | Yes | Moderate acute tubular necrosis | + | Not detected | Yes | 88 | 209 | Diffuse alveolar damage |
3a | M/76 | Yes | Severe acute tubular necrosis | + | Not detected | Yes | 153 | 179 | Diffuse alveolar damage |
4 | F/81 | Yes | Mild acute tubular necrosis | + | Not detected | Minimal | 107 | 131 | Diffuse alveolar damage |
5 | M/44 | Yes | Severe acute tubular necrosis | - | not detected | yes | 107 | 315 | Diffuse alveolar damage |
6 | M/79 | Yes | Moderate acute tubular necrosis | + | not detected | yes | 179 | 238 | Diffuse alveolar damage |
7 | F/91 | Yes | Minimal | + | not detected | yes | 75 | 97 | Diffuse alveolar damage |
Heavy abnormal myeloid infiltrate in the kidney (the patient had history of myelodysplastic syndrome).