Table 5.

Effect on complications necessitating use of antibiotics and pneumonia of zanamivir and oseltamivir¹

Drug and patients treated	Complications necessitating use of antibiotics						Pneumonia
	ITT population			Influenza positive			ITT population			Influenza positive
Placeb ogroup (%)	Treatment group (%)	Odds ratio (95% CI)	Placebo group (%)	Treatment group (%)	Odds ratio (95% CI)	Placebo group (%)	Treatment group (%)	Odds ratio (95% CI)	Placebo group (%)	Treatment group (%)	Odds ratio (95% CI)
Zanamivir
“All” individuals	18	13	0·71 (0·56 to 0·90)	18	13	0·82 (0·61 to 1·10)	1	<1	0·49 (0·21 to 1·06)	2	<1	0·43 (0·15 to 1·10)
High-risk individuals	..	..	..	24	15	0·55 (0·24 to 1·23)	4	3	0·90 (0·21 to 3·62)	4	3	0·69 (0·10 to 3·64)
High-risk children and adults	25	16	0·57 (0·31 to 1·03)	24	13	0·49 (0·23 to 1·04)	..	..	..	..	..	..
Oseltamivir
“All” individuals	..	..	..		..	..	..	..	..	2	<1	0·37 (0·15 to 0·86)
Healthy	..	..	..	5	2	0·32 (0·16	..	..	..	1	<1	0·15 (0·06
individuals						to 0·59)						to 0·72)
High-risk individuals	..	..	..	18	12	0·62 (0·40 to 0·94)	..	..	..	2	2	0·76 (0·24 to 2·23)