Table.
Serum cytokine concentrations of patients with influenza subtype H5N1, patients with influenza A and B infection, and healthy controls
|
Serum cytokine concentrations (ng/L) |
||||||
|---|---|---|---|---|---|---|
| IP-10 | MCP-1 | MIG | RANTES | Interleukin 8 | ||
| Patient 1*with influenza A (H5N1) | ||||||
| 6 days after illness onset | 36000 | 644 | 5100 | 24000 | 30 | |
| 8 days after illness onset |
>50000 |
2316 |
17000 |
23000 |
90 |
|
| Patient 2†influenza A (H5N1) | ||||||
| 3 days after illness onset | 16000 | 85 | 1400 | 29000 | 41 | |
| 5 days after illness onset |
1300 |
80 |
343 |
>50000 |
22 |
|
| Influenza A or B controls‡ | ||||||
| 1–3 days after symptoms | ||||||
| Median | 2650 | 330 | 600 | NA§ | 9 | |
| Mean | 3582 | 520 | 675 | NA§ | 11 | |
| SD | 3952 | 599 | 426 | NA§ | 8 | |
| Range | 490–11000 | 100–1700 | 330–1500 | 20000–>50000 | 3–24 | |
| 9–10 days after symptoms | ||||||
| Median | 335 | 125 | 250 | NA§ | 9 | |
| Mean | 332 | 131 | 260 | NA§ | 37 | |
| SD | 104 | 47 | 86 | NA§ | 70 | |
| Range |
190–450 |
75–200 |
170–410 |
14000–>50000 |
6–180 |
|
| Healthy controls¶ | ||||||
| Median | 159 | 76 | 198 | 17884 | 11 | |
| Mean | 202 | 107 | 238 | 18143 | 19 | |
| SD | 83 | 63 | 104 | 712 | 16 | |
| Range |
129–301 |
43–181 |
129–363 |
17285–19156 |
8-44 |
|
33-year-old man.
8-year-old boy.
n=6; age-range 23–41 years.
Mean, median and SD cannot be calculated since some results are beyond the upper range of assay.
n=5; age-range 21–37 years.