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. Author manuscript; available in PMC: 2020 Sep 1.
Published in final edited form as: Cancer Res. 2020 Jan 16;80(5):1078–1087. doi: 10.1158/0008-5472.CAN-19-2039

Table 2. Top genes from MIP.

Top 9 immune genes that are significantly increased in patients with good DSS after Benjamini-Hochberg correction and correlation of these genes with qmIF data for stromal density of CD3, CD3+CD8+, and CD68+ as well as ratio of CD8/CD68. Values in bold are different from 0 with a significance level alpha=0.05 using Benjamini-Hochberg correction.

Differential expression Correlation with Density
Gene Fold Change BH p value CD8/CD68 Stroma CD3+CD8+ Stroma CD68+ Stroma CD3+ Stroma

PTPRC 1.07 0.0399 0.05 0.17 0.12 0.3
CCL5 1.19 0.0399 0.21 0.36 0.03 0.41
CD2 1.05 0.0399 0.07 0.24 0.14 0.36
CD27 1.21 0.04 0.04 0.2 0.16 0.31
CXCL9 1.56 0.0459 0.19 0.33 0.04 0.45
CD8A 1.26 0.0459 0.16 0.35 0.11 0.39
CXCR3 1.11 0.0459 0.19 0.36 0.06 0.4
CXCL11 1.39 0.0459 0.2 0.38 0.05 0.42
LCK 1.14 0.0459 −0.03 0.12 0.21 0.24