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. 2016 Sep 9;73(6):598–606. doi: 10.1016/j.jinf.2016.09.001

Table 3.

Multiple logistic regression analysis showing associations between duration of hospitalisation (in days) and other variables, for all patients (n = 306).

Variable Ratio 95% CI p Value
Ct valuea 0.94 0.92 0.97 <0.001
Agea 1.02 1.01 1.04 <0.001
Duration of illness prior to admission, days 0.99 0.93 1.07 0.965
Sex (reference group: female) 0.80 0.58 1.11 0.181
Influenza vaccine (reference group: no) 0.94 0.67 1.31 0.700
Comorbidity (reference group: none) 1.47 1.05 2.07 0.025
Antibiotics prior to admission (reference group: none) 1.12 0.78 1.60 0.544
Current smoker (reference group: no) 1.11 0.78 1.58 0.563
Bacterial detection (reference group: no) 1.78 1.18 2.67 0.006
Clinical group
Asthma (reference group)
IECOPD 1.16 0.72 1.85 0.538
Pneumonia 1.44 0.79 2.63 0.236
ILI/bronchitis 0.46 0.21 0.98 0.044
Virus type
Influenza (reference group)
Rhino/enterovirus 0.92 0.62 1.38 0.692
Other virusesb 1.12 0.74 1.70 0.588

Abbreviations: Ct, real-time PCR Cycle threshold (a low Ct value represents a high viral load and vice versa); IECOPD, infective exacerbation of COPD; CAP, community acquired pneumonia; ILI, Influenza-like illness; CI, confidence interval.

Note: For each unit decrease in Ct value (i.e. increase in viral load), there is a 6% increase in expected days in hospital. Likewise, for each additional year of age, length of stay increases by 2%. The presence of at least one of any recorded comorbidity (cardiovascular, renal or liver disease, malignancy or diabetes) increases length of stay by 47% relative to people without any of these comorbidities. The detection of bacteria was associated with a 78% increase in length of stay. Patients with ILI/bronchitis had a length of stay 46% shorter than those with asthma.

p values highlighted in bold are statistically significant (i.e., p <0.05).

a

Variables are mean-centred.

b

Includes; Respiratory Syncytial Virus, parainfluenza 1–4, human metapneumovirus, human coronavirus and adenovirus.