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. 2019 Nov 13;117:37–53. doi: 10.1016/j.molimm.2019.10.017

Fig. 4.

Fig. 4

Protein-protein interaction networks of deiminated protein hits identified in EVs of llama (Lama glama) serum. Reconstruction of protein-protein interactions based on known and predicted interactions using STRING analysis. Due to annotations for camelids not being present in STRING, proteins are based on corresponding human protein identifiers. A. Coloured nodes represent query proteins and first shell of interactors. B. Biological GO processes are highlighted as follows: red = response to stress; blue = cytoskeleton organisation; green = vesicle mediated transport. Coloured lines indicate whether protein interactions are identified via known interactions (curated databases, experimentally determined), predicted interactions (gene neighbourhood, gene fusion, gene co-occurrence) or via text mining, co-expression or protein homology (see colour key for connective lines in A).