Table 1.
Summary of SARS-CoV-related proteins with known structures
| Proteins | Protein size (aa) | Location in the genome (bp) | Description of the related structure | References |
|---|---|---|---|---|
| Structural proteins (2/4) | ||||
| S | 1255 | ORF2 (21492–25259) | Fusion core, RBD-ACE2 complex, RBD-Ab complex | [38], [39], [51], [76] |
| N | 422 | ORF9a (28120–29388) | N-terminal domain | [75] |
| Nsps (7/16) | ||||
| Nsp3 | 1922 | ORF1a (2719–8484) | PL2pro | [82] |
| Nsp5 | 308 | ORF1a (9985–10902) | +, 3CLpro | [41] |
| Nsp7 | 83 | ORF1a (11773–12021) | + | [46] |
| Nsp8 | 198 | ORF1a (12022–12615) | + | [46] |
| Nsp9 | 113 | ORF1a (12616–12954) | +, ssRNA binding subunit | [61], [83] |
| Nsp10 | 139 | ORF1a (12955–13371) | + | [79], [81] |
| Nsp15 | 346 | ORF1b (19551–20588) | +, endoribonuclease | [80] |
| Accessory proteins (2/8) | ||||
| ORF7a | 122 | ORF7a (27273–27261) | +, Ig-like | [85] |
| ORF9b | 98 | ORF9b (28130–28426) | + | [86] |