Fig. 2.
Lipid metabolism at the pathogen-containing vacuole. The various effectors and enzymes are drawn in the vacuolar membrane. However, their exact location relative to the membrane is, in most cases, unknown. PLA: phospholipase A1 or A2; PLC: phospholipase C; PLD: phospholipase D; PL: phospholipid; PA: phosphatidic acid; DAG: diacylglycerol; Sph: sphingosine; S1P: sphingosine-1-phosphate; RSV: respiratory syncytial virus; CMV: cytomegalovirus; Chol: cholesterol; LDL: low-density lipoprotein; EspF: Escherichia coli effector molecule F; SapM: M. tuberculosis effector molecule; IpgD: Shigella flexneri effector molecule; SseJ: Salmonella SPI-2 effector molecule; Lda: Lipid droplet-associated Chlamydial effector proteins. For other abbreviations: see legend to Fig. 1.