Extended Data Fig. 5. Combined inhibition of mitochondrial and peroxisomal FAO with increased in vivo dosage of etomoxir and thioridazine in support of figure 5.

Absolute number of live splenic NP⁺ GCBC (a) and naïve NP⁻ B cells (b) and MFI of 2-NBDG of GCBC after 30min 2-NBDG in vitro pulse (c) of mice at d14 post NP-CGG immunization and in vivo treatment at d9, d11 and d13 with 22 mg/kg etomoxir and 11mg/kg thioridazine or vehicle only as in Fig. 5c–e. Every dot represents and individual mouse and graphs are mean +/−SEM; ns = not significant; ****p<0.0001 by unpaired, two-tailed t-test.