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Results of antibody detection in clinical serum samples using the ICTS and the FAVN testa.
| FAVN test |
|||||
|---|---|---|---|---|---|
| ≥0.5 IU/ml | <0.5 IU/ml | Negative | Total | ||
| ICTS | Positive | 331 | 7 | 0 | 338 |
| Negative | 35 | 245 | 138 | 418 | |
| Total | 366 | 252 | 138 | 756 | |
Relative to FAVN test, specificity of ICTS: (245 + 138)/(252 + 138) = 98.2%; sensitivity of ICTS: 331/(331 + 35) = 90.4%; Po = (383 + 331)/756 = 94.4%; Pe = [(366/756) × (338/756) + (390/756) × (418/756)] = 0.502; kappa = (Po − Pe)/(1 − Pe) = 0.4424/0.498 = 0.888.
