. 2008 Mar 31;27(5):394–406. doi: 10.1016/j.trac.2008.03.006

Table 5.

DNA hybridization assays using nanoparticles (NPs)

NPs	Detection system	Limit of detection (LOD)	Ref.
Au	Light scattering	0.1 pM	[72]
		10 fM	[73]
Au	Fluorescence quenching of a rhodamine derivative	2 nM	[74]
Au	Chemiluminescence	0.1 pM	[75]
Au	Optical scanner	0.1 μM	[76]
Au	Surface-plasmon resonance	4.8 pM	[77]
Au	Quartz-crystal microbalance	1 pM	[78]
Au	Electrochemical	0.1 nM	[79]
Ag	Fluorimetry	50 nM	[80]
Pt	Electrochemical	1 nM	[81]
Tb-chelate silica	FRET^a	0.1 pM	[82]
Ru-chelate silica	Electrogenerated chemiluminescence	0.1 pM	[83]
Quantum dots (QDs)	FRET^a	–	[84]
Quantum dots (QDs)	FRET^a	–	[85]
Quantum dots (QDs)	Fluorimetry	–	[87]

FRET: Fluorescence resonance energy transfer.