Table 2.
Denosumab/Alendronate Sequence | ||
---|---|---|
Denosumab Year 1 (N = 126) | Alendronate Year 2 (N = 115) | |
Race/ethnicity—white, n (%) | 115 (91) | 107 (93) |
Age, mean (SD), years | 65.1 (7.6) | 65.1 (7.4) |
Years since menopause, mean (SD) | 18.2 (11.4) | 17.9 (10.9) |
BMD T-score at the start of each year, mean (SD) | ||
Lumbar spine | –2.04 (1.16) | –1.61 (1.29) |
Total hip | –1.60 (0.74) | –1.38 (0.74) |
Femoral neck | –2.01 (0.55) | –1.84 (0.6) |
Prior osteoporotic fracture, n (%) | 47 (37.3) | 41 (35.7) |
N = number of participants randomized (year 1) or crossed over (year 2); n = number of participants with the characteristic of interest.
Abbreviations: BMD, bone mineral density SD, standard deviation.