Table 3.

Circulating levels of FSTL3 and of total IGF-1/intact IGFBP-3 ratio in histologic lesions within NAFLD subjects (n = 31).

Histologic lesion		N	FSTL3 (ng/ml)	Total IGF-1 to Intact IGFBP-3 ratio
Steatosis grade	≤ 33%	20	13.3 ± 1.8	0.160 (0.139, 0.229)
	>33%	11	15.6 ± 2.8	0.136 (0.110, 0.277)
	P-value*		.02	.22#
Lobular inflammation	Absent	19	13.1 ± 1.4	0.177 ± 0.068
	Present	12	15.9 ± 2.9	0.150 ± 0.064
	P-value*		.003	.34
Portal inflammation	None to minimal	18	13.0 ± 1.6	0.183 ± 0.068
	Greater than minimal	13	15.7 ± 2.7	0.143 ± 0.060
	P-value*		.005	.15
Ballooning	Absent	6	13.0 ± 1.4	0.219 ± 0.075
	Present	25	14.5 ± 2.6	0.156 ± 0.061
	P-value*		.23	.08
Fibrosis	Absent	10	13.4 ± 1.9	0.205 ± 0.074
	Present	21	14.6 ± 2.7	0.147 ± 0.055
	P-value*		.25	.04

Data are presented as mean ± SD if normally distributed, and as median with (first and third quartile) if not normally distributed.

#P-value referring to the comparison of parameters that are not normally distributed.

*Independent sample t-test or Mann–Whitney test.