TABLE 3.
Comorbidity of MERS-CoV cases at KAMC-Riyadh (mid-June to mid-September, 2015)
| Variable | Patients (N=87) | HCWs (N=43) | Overall (N=130) | P value |
|---|---|---|---|---|
| Any comorbid diseases | ||||
| No | 1 (1%) | 25 (58%) | 26 (20%) | <.001 |
| Yes | 86 (99%) | 18 (42%) | 104 (80%) | |
| Number of comorbid diseases | ||||
| Mean (SD) | 5.6 (2.3) | 2.0 (1.1) | 4.9 (2.5) | <.001 |
| 1–3 diseases | 16 (19%) | 16 (89%) | 32 (31%) | <.001 |
| 4–6 diseases | 41 (48%) | 2 (11%) | 43 (41%) | |
| ≥7 diseases | 29 (34%) | 0 (0%) | 29 (28%) | |
| Respiratory comorbid diseases | ||||
| Any respiratory disease | 22 (25%) | 6 (14%) | 28 (22%) | .14 |
| Asthma | 10 (12%) | 3 (7%) | 13 (10%) | .54 |
| Chronic obstructive pulmonary disease | 14 (16%) | 3 (7%) | 17 (13%) | .15 |
| Bronchiectasis | 3 (3%) | 0 (0%) | 3 (2%) | .55 |
| Tuberculosis | 5 (6%) | 0 (0%) | 5 (4%) | .17 |
| Allergic rhinitis | 1 (1%) | 2 (5%) | 3 (2%) | .25 |
| Other chronic respiratory disease | 6 (7%) | 1 (2%) | 7 (5%) | .42 |
| Other comorbid diseases | ||||
| Hypertension | 70 (81%) | 4 (9%) | 74 (57%) | <.001 |
| Diabetes | 68 (78%) | 3 (7%) | 71 (55%) | <.001 |
| Heart disease | 45 (52%) | 0 (0%) | 45 (35%) | <.001 |
| Chronic kidney disease | 38 (44%) | 0 (0%) | 38 (29%) | <.001 |
| Hemodialysis | 13 (15%) | 0 (0%) | 13 (10%) | .01 |
| Immunosuppressive disease | 36 (41%) | 0 (0%) | 36 (28%) | <.001 |
| Neurologic disease | 24 (28%) | 1 (2%) | 25 (19%) | <.01 |
| Stroke | 21 (24%) | 1 (2%) | 22 (17%) | <.01 |
| Cancer | 19 (22%) | 0 (0%) | 19 (15%) | <.01 |
| Previous surgeries | 15 (17%) | 3 (7%) | 18 (14%) | .11 |
| Dyslipidemia | 17 (20%) | 0 (0%) | 17 (13%) | <.01 |
| Hypothyroidism | 12 (14%) | 3 (7%) | 15 (12%) | .38 |
| Other metabolic disease | 9 (10%) | 2 (5%) | 11 (9%) | .34 |
| Blood disease | 7 (8%) | 3 (7%) | 10 (8%) | >.99 |
| Urinary tract infection | 8 (9%) | 2 (5%) | 10 (8%) | .50 |
| Chronic liver disease | 7 (8%) | 1 (2%) | 8 (6%) | .27 |
| Benign prostatic hyperplasia | 7 (8%) | 0 (0%) | 7 (5%) | .10 |
| Psychiatric disease | 4 (5%) | 0 (0%) | 4 (3%) | .30 |
| Rheumatoid | 1 (1%) | 0 (0%) | 1 (1%) | >.99 |
| Other chronic disease | 17 (20%) | 4 (9%) | 21 (16%) | .14 |
| Bed bound | 8 (9%) | 0 (0%) | 8 (6%) | .05 |
| Pregnancy | 0 (0%) | 1 (2%) | 1 (1%) | .33 |
NOTE. The column heads represent the maximum number; the denominator was sometimes lower when data were missing. HCW, healthcare worker; KAMC, King Abdulaziz Medical City; MERS-CoV, Middle East respiratory syndrome coronavirus.