FIG 2.

Observational Health Data Sciences and Informatics (OHDSI) structure and analysis flow diagram. Behind each institution’s firewall, source data are converted to standard Observational Medical Outcomes Partnership (OMOP) format through an extract-transform-load (ETL) process from which large-scale analyses can be executed. Aggregate results and summary statistics are shared across the firewall with the coordinating center, which serves multiple organizational roles including the completion of these analyses Used with permission from OHDSI. CDM, common data model.