Table 2.
Results of Univariable Analysis Evaluating the Effect of Each Predictive Factor on Anterior Lamina Cribrosa (ALCS) Displacement over Time (β) in Glaucoma eyes
| Parameter | Effect on Change over Time (slope) | |
|---|---|---|
| β (95% CI) | P | |
| Age (per 10 year older) | −0.75 (−1.71, 0.21) | 0.124 |
| Gender (Female) | 0.26 (−1.91, 2.43) | 0.792 |
| Race: African American | −0.12 (−2.44, 2.19) | 0.916 |
| Baseline IOP (per mm Hg higher) | 0.18 (−0.06, 0.42) | 0.142 |
| Average IOP (per mm Hg higher) | 0.34 (0.07, 0.61) | 0.013 |
| Peak IOP (per mm Hg higher) | 0.29 (0.07, 0.51) | 0.009 |
| IOP change (per mm Hg higher) | 0.36 (0.04, 0.68) | 0.029 |
| CCT (per 10 μm thinner) | −0.25 (−0.5, −0.01) | 0.042 |
| Choroidal Thickness (per 10 μm thinning) | −0.27 (−0.5, −0.03) | 0.025 |
| Baseline SAP-MD (per dB lower) | −0.10 (−0.29, 0.08) | 0.283 |
| Baseline SAP-PSD (per dB higher) | −0.19 (−0.49, 0.1) | 0.196 |
| CH (per 1 mm Hg lower) | 0.63 (−0.1, 1.37) | 0.093 |
| CRF (per 1 mm Hg lower) | −0.33 (−0.86, 0.2) | 0.225 |
| Axial length (per 1 mm higher) | 0.24 (−0.64, 1.12) | 0.597 |
CCT: central corneal thickness; CH: corneal hysteresis; CI: confidence interval; CRF: corneal resistance factor; IOP: intraocular pressure; MD: mean deviation; SAP: standard automated perimetry
Coefficient β corresponds to the effect on change over time. Positive values correspond to posterior ALCS displacement over time while negative values correspond to anterior ALCS displacement over time
P<0.05 are shown as bold