. Author manuscript; available in PMC: 2021 Apr 1.

Published in final edited form as: Ann Allergy Asthma Immunol. 2020 Jan 13;124(4):342–349. doi: 10.1016/j.anai.2020.01.001

Table 3:

Examining potential effect modification in the association between race and binary allergic outcomes at age 10.

Effect Modifier	Sensitized to ≥1 sIgE	SPT+	Eczema	Asthma	PC₂₀≤25 mg/ml

	Interaction p-value¹
Mode of delivery	0.21	0.41	0.95	0.11	0.93
First born child	0.67	0.095³	0.75	0.71	0.25
Child sex	0.71	0.94	0.57	0.93	0.091⁴
Prenatal indoor dog(s)	<0.05²	0.18	0.76	0.23	0.93
Ever breastfed their child	0.99	0.20	0.55	0.80	0.31

Interaction term added to the fully-adjusted imputation model, with IPWs to account for loss to follow-up (N=481).

Significant racial difference in dog-exposed children only: OR (95% CI)=0.68 (0.29, 1.61), p=0.39; 11.18 (3.34, 37.41), p<0.05; in those unexposed and exposed to dogs, respectively.

Non-significant racial differences in both subgroups: OR (95% CI)=1.72 (0.50, 5.84), p=0.39; 0.71 (0.26, 1.94), p=0.50; in those who are and are not first born children, respectively.

⁴

Significant racial difference in males only: OR (95% CI)=3.46 (1.50, 7.99), p=0.004; 1.14 (0.43, 3.05), p=0.79; in males and females, respectively.