Table 1.

Clinical and Demographic data of IgG4-RD cohort.

IgG4-RD Cohort (n = 100)
Demographic Data
Age at Onset (median, IQR)	55 (4–83)
Age at Diagnosis (median, IQR)	61 (4–84)
Sex (n, % male)	68, 68%
Ethnicity
Caucasian (n, %)	69, 69%
Asian (n, %)	12, 12%
Hispanic (n, %)	5, 5%
African American (n, %)	4, 4%
Other(n, %)	10, 10%
Clinical Data
Clinically Active (n, %)	100, 100%
IgG4-RD-RI (median, IQR)	4 (0–20)
On Treatment (n, %)	14, 14%
Organ Distribution
Multi-organ Involvement (n, %)	68, 68%
Number of Organs Involved (median, IQR)	3 (1–10)
Lymph Nodes (n, %)	41, 41%
Submandibular Gland (n, %)	48, 48%
Pancreas (n, %)	32, 32%
Parotid Gland (n, %)	26, 26%
Lacrimal Gland (n, %)	31, 31%
Lungs (n, %)	18, 18%
Retroperitoneum (n, %)	20, 20%
Kidney (n, %)	21, 21%
Bile Ducts (n, %)	14, 14%
Laboratory Parameters
Elevated Total IgG, >1,295 mg/dL (n, %)	63, 63%
Elevated serum IgG1, >928.6 mg/dL (n, %)	43, 43%
Elevated serum IgG2, >700.3 mg/dL (n, %)	39, 39%
Elevated serum IgG3, >176.1 mg/dL (n, %)	36, 36%
Elevated serum IgG4, >86.4 mg/dL (n, %)	76, 76%
Elevated serum IgE, >114 kU/L (n, %)	54, 54%
Low serum IgM, <53 mg/dL (n, %)	39, 39%
Hypocomplementemia, C3 < 81 mg/dL or C4 < 12 mg/dL (n, %)	30, 30%
Elevated C-reactive protein, >8.0 mg/L (n, %)	35, 35%
Elevated erythrocyte sedimentation rate, >13 mm/hr (n, %)	63, 63%