Table 5.

Epidermal or sweat gland nerve fiber densities in cases and historical controls.

Part A. Quantitative comparison of epidermal nerve fiber densities
Group	Mean density (fibers/mm of epidermal length)	95% Confidence interval	p‐value*
Paresthesia cases (n=37)	4.70	3.95 ‐ 5.45	< 0.0001
Historical controls (n=128)	8.32	7.86 ‐ 8.77
* From generalized linear models regression analysis adjusted for age and gender.

Part B. Categorical comparison of the prevalence of abnormally reduced nerve fiber densities based on a composite evaluation of epidermal and sweat gland nerve fiber densities.
	Composite nerve fiber density measure
Group	Abnormal (n, (%))	Normal	Total	p-value, Fisher’s exact test
Paresthesia cases	21 (57%)	16 (43%)	37	< 0.0001
Historical controls (n=128)	5 (3.9%)	123 (96%)	128