Table 2.
Clinical evaluation of PPPCD families.
| PPPCD Affected | Unaffected | P Value | |||
|---|---|---|---|---|---|
| Mean | SD | Mean | SD | ||
| Refractive | |||||
| Ref Sphere (D) | −0.42 | 2.54 | −2.08 | 3.26 | 0.12 |
| Ref Cylinder (D) | −0.79 | 0.66 | −0.48 | 0.45 | 0.1 |
| CDVA (decimal) | 0.1 | 0.05 | 1.02 | 0.06 | 0.43 |
| Tomographic | |||||
| Anterior Km (D) | 44.33 | 1.93 | 43. 94 | 1.35 | 0.67 |
| Topo Cylinder (D) | −0.98 | 0.5 | −1.13 | 0.44 | 0.2 |
| CCT (μm) | 528.65 | 30.69 | 539.4 | 25.48 | 0.24 |
| Thinnest (μm) | 517.75 | 32.81 | 530.15 | 28.27 | 0.21 |
| Kmax (D) | 44.83 | 1.96 | 44.51 | 1.43 | 0.74 |
| Wavefont | |||||
| Corneal Total HOA (μm) | 0.59 | 0.37 | 0.46 | 0. 1 | 0.35 |
| Corneal Coma (μm) | 0.33 | 0.18 | 0.31 | 0.1 | 0.95 |
| Corneal Sph (μm) | 0.22 | 0.18 | 0.22 | 0.07 | 0.11 |
| Endothelial specular microscopy | |||||
| CD (cells/mm2) | 2563 | 708.7 | 2572 | 344.83 | 0.84 |
| CV | 43 | 40.3 | 33 | 5.56 | 0.12 |
| Hexagonality (%) | 61 | 10.13 | 61 | 9.26 | 0.48 |
| Ocular abberometry | |||||
| Strehl Ratio (PSF) | 0.37 | 0.15 | 0.39 | 0.17 | 0.85 |
| OSI | 1.24 | 1.19 | 0.82 | 0.53 | 0.62 |
| Biomechanical | |||||
| CH (mm Hg) | 10.32 | 1.44 | 9.85 | 1.52 | 0.26 |
| CRF (mm Hg) | 10.77 | 1.32 | 9.93 | 1.24 | 0.02* |
| Intraocular Pressure | |||||
| IOP (mm Hg) | 14.6 | 3.5 | 13.25 | 2.15 | 0,22 |
Ref: refractive; D: diopters; CDVA: corrected distance visual acuity; dec: decimal scale; Km: mean keratometry; Topo: topographic; CCT: central corneal thickness; Thinnest: thinnest pachymetric point; Kmax: maximum keratometry; HOA: higher order aberrations; Sph: spherical aberration; CD: cell density; CV: coefficient of variation; 6A: hexagonality; PSF: point spread function; OSI: ocular scatter index; CH: corneal hysteresis; CRF: corneal resistance factor].
*
statistically significant differences.