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. 2020 Mar 1;27(3):255–270. doi: 10.5551/jat.49106

Table 2. Dilatation ratio for AEBP1 knockdown in AAA rat models.

Group Day 0 (mm) Day 28 (mm) Dilatation ratio (%)
sham 1.18 ± 0.14 1.21 ± 0.13 3.43 ± 4.75a
control 1.20 ± 0.13 2.44 ± 0.19 104.19 ± 14.96ab
con + AV 1.19 ± 0.10 2.41 ± 0.16 103.64 ± 9.53ab
con + shAEBP1 1.18 ± 0.10 1.90 ± 0.13 62.60 ± 43.38b

The diameters of infrarenal abdominal aorta in sham, control, con + AV and con + shAEBP1 were measured by vernier caliper on day 0 and day 28 after surgery. Group sham, rats were opened as a control; Group control, rats received elastase perfusion (20 U/ml) (Solarbio, Beijing, China) for 15 min; Group con + AV, rats received elastase perfusion and 40ul empty adenovirus (5x1011/ml) was injected into the intra-adventitial via at least four positions; Group con + shAEBP1, rats received elastase perfusion and adenovirus with AEBP1 shRNA.

Dilation ratio (%) was calculated according to the following formula: Dilation ratio (%) = (diameter of D28-diameter of D0)/ diameter of D0 x 100%.

a

p < 0.01 vs group con + shAEBP1.

b

p < 0.01 vs group sham.