Table 2. Dilatation ratio for AEBP1 knockdown in AAA rat models.
Group | Day 0 (mm) | Day 28 (mm) | Dilatation ratio (%) |
---|---|---|---|
sham | 1.18 ± 0.14 | 1.21 ± 0.13 | 3.43 ± 4.75a |
control | 1.20 ± 0.13 | 2.44 ± 0.19 | 104.19 ± 14.96ab |
con + AV | 1.19 ± 0.10 | 2.41 ± 0.16 | 103.64 ± 9.53ab |
con + shAEBP1 | 1.18 ± 0.10 | 1.90 ± 0.13 | 62.60 ± 43.38b |
The diameters of infrarenal abdominal aorta in sham, control, con + AV and con + shAEBP1 were measured by vernier caliper on day 0 and day 28 after surgery. Group sham, rats were opened as a control; Group control, rats received elastase perfusion (20 U/ml) (Solarbio, Beijing, China) for 15 min; Group con + AV, rats received elastase perfusion and 40ul empty adenovirus (5x1011/ml) was injected into the intra-adventitial via at least four positions; Group con + shAEBP1, rats received elastase perfusion and adenovirus with AEBP1 shRNA.
Dilation ratio (%) was calculated according to the following formula: Dilation ratio (%) = (diameter of D28-diameter of D0)/ diameter of D0 x 100%.
p < 0.01 vs group con + shAEBP1.
p < 0.01 vs group sham.