Table 2. Risk factors associated with ICAS status and distribution.
| Variables | ICAS Status (n = 3678) |
p-value | Distribution of ICAS (n = 513) |
p-value | ||
|---|---|---|---|---|---|---|
| Present (n = 641) |
Absent (3037) |
Anterior (n = 400) |
Posterior (n = 113) |
|||
| Age (year), M ± SD | 66 ± 11 | 62 ± 13 | < 0.001 | 64 ± 12 | 69 ± 11 | < 0.001 |
| Male, n (%) | 327 (51.0) | 1256 (41.4) | 0.004 | 204 (51) | 59 (52.2) | 0.820 |
| Risk factors, n (%) | ||||||
| Hypertension | 464 (73.1) | 1663 (55.3) | < 0.001 | 271 (68.3) | 84 (75.7) | 0.132 |
| Diabetes | 202 (31.5) | 614 (20.2) | < 0.001 | 108 (27.0) | 39 (34.5) | 0.128 |
| Hyperlipidemia | 398 (62.1) | 1837 (60.5) | 0.450 | 233 (58.3) | 71 (62.8) | 0.381 |
| Atrial fibrillation | 12 (2.0) | 73 (2.5) | 0.393 | 7 (1.8) | 1 (1.0) | 0.531 |
| CAD | 81 (12.7) | 252 (8.4) | 0.001 | 37 (9.3) | 18 (16.2) | 0.038 |
| Previous stroke | 101 (15.8) | 229 (7.5) | < 0.001 | 35 (8.8) | 26 (23.0) | < 0.001 |
| history | ||||||
| Smoking | 221 (34.5) | 883 (29.1) | 0.007 | 134 (33.5) | 35 (31.0) | 0.614 |
| Drinking | 170 (26.5) | 798 (26.3) | 0.898 | 105 (26.3) | 33 (29.2) | 0.532 |
| BMI (kg/m2) | 25.55 ± 3.58 | 25.83 ± 3.88 | 0.088 | 25.69 ± 3.51 | 25.44 ± 3.47 | 0.574 |
| Glucose (mmol/L) | 6.64 ± 2.22 | 6.15 ± 1.65 | < 0.001 | 6.52 ± 2.18 | 6.67 ± 2.07 | 0.496 |
| TC (mmol/L) | 4.94 ± 1.07 | 4.91 ± 0.99 | 0.589 | 4.94 ± 1.07 | 4.88 ± 1.06 | 0.985 |
| LDL-C (mmol/L) | 2.93 ± 0.88 | 2.87 ± 0.83 | 0.074 | 2.91 ± 0.86 | 2.93 ± 0.90 | 0.816 |
| HDL-C (mmol/L) | 1.36 ± 0.37 | 1.42 ± 0.37 | < 0.001 | 1.38 ± 0.39 | 1.32 ± 0.31 | 0.137 |
| TG (mmol/L) | 1.41 ± 0.84 | 1.37 ± 0.83 | 0.249 | 1.39 ± 0.87 | 1.35 ± 0.59 | 0.622 |
| Scr (ummol/L) | 89.35 ± 24.01 | 85.21 ± 17.88 | < 0.001 | 87.07 ± 20.81 | 91.22 ± 23.98 | 0.071 |
| UMA (mg/L) | 13.1 (30.2) | 12.4 (22.7) | 0.697 | 12.9 (24.7) | 11.4 (25.9) | 0.377 |
| Bp (mmHg) | ||||||
| Sp | 140 ± 19 | 133 ± 17 | < 0.001 | 139 ± 18 | 141 ± 20 | 0.295 |
| Dp | 75 ± 11 | 76 ± 11 | 0.008 | 75 ± 11 | 75 ± 10 | 0.952 |
| eGFR (ml/min/1.73 m2) | 70.64 ± 15.94 | 73.87 ± 15.07 | < 0.001 | 73.10 ± 15.30 | 68.09 ± 15.97 | 0.002 |
| eGFR as ≥ 90 | 82 (12.8) | 470 (15.5) | < 0.001 | 64 (16.0) | 10 (8.8) | 0.017 |
| category 60–89 | 405 (63.2) | 2016 (66.4) | 264 (66.0) | 70 (61.9) | ||
| variable, 45–59 | 117 (18.3) | 482 (15.9) | 57 (14.3) | 23 (20.4) | ||
| n (%) < 45 | 37 (5.8) | 69 (2.3) | 15 (3.8) | 10 (8.8) | ||
CAD: coronary heart disease; TC: total cholesterol; LDL-C: Low-density lipoprotein cholesterol; HDL-C: High-density lipoprotein cholesterol; TG: triglyceride; Scr: serum creatinine; UMA: urinary microalbumin; Bp: blood pressure; Sp: Systolic pressure; Dp: Diastolic pressure