Supplementary Table 8. Association analyses of rs852426 with stroke in the nested case-control study.
| Stratification | Group | WT/HT/MT |
OR (95% CI) |
||
|---|---|---|---|---|---|
| Additive model | Dominant model | Recessive model | |||
| Total Population | TT/TC/CC | ||||
| Case | 537/280/43 | 0.996 (0.859–1.154)a | 1.040 (0.865–1.250)a | 0.821 (0.555–1.215)a | |
| Control | 1232/598/130 | P = 0.958a | P = 0.678 | P = 0.324 | |
| Drinking | TT/TC/CC | ||||
| Case | 155/65/9 | 0.801 (0.591–1.087)b | 0.807 (0.557–1.168)b | 0.560 (0.236–1.327)b | |
| Control | 352/195/36 | P = 0.154b | P = 0.255 | P = 0.188 | |
| Non-drinking | TT/TC/CC | ||||
| Case | 383/214/34 | 1.080 (0.910–1.281)b | 1.150 (0.927–1.427)b | 0.926 (0.593–1.446)b | |
| Control | 880/403/94 | P = 0.380b | P = 0.204 | P = 0.735 | |
WT, wild type; HT, heterozygote; MT, mutant type; OR, odds ratio; CI, interval confidence.
a
Adjusted for age, gender, BMI, HDL-C, LDL-C, TC, TG, smoking status, drinking status, T2DM and hypertension.
b
Adjusted for age, gender, BMI, HDL-C, LDL-C, TC, TG, smoking status, T2DM and hypertension.