Table 3. Association of rs852426 and drinking with stroke in the follow-up study.
| Interaction | Model 1 | Model 2 | |
|---|---|---|---|
| Drinking* rs852426 | |||
| HR (95% CI) | 0.618 (0.349, 1.093) | 0.541 (0.291, 0.994) | |
| p | 0.098 | 0.048 | |
| Drinking+rs852426 | |||
| RERI | HR (95% CI) | −0.705 (−1.377, −0.237) | −0.907 (−1.411, −0.404) |
| p | 3.164×10−3 | 4.108×10−4 | |
| AP | −0.994 | −1.398 | |
| SI | 0.704 | −0.630 |
HR, hazard ratio; CI, confidence interval; RERI, relative excess risk due to interaction; AP, attributable proportion due to interaction; SI, synergy index
Model 1 did not adjust any covariates.
Model 2 adjusted for age, gender, BMI, HDL-C, LDL-C, TC, TG, smoking status, T2DM and hypertension.